MEDIA RELEASE
Schlieren-Zurich, November 14, 2012
Prionics: New test to combat scrapie and mad cow disease in sheep and
goats
An innovative new test is now available to detect TSE (scrapie and mad cow
disease) in sheep and goats. With the Prionics®-Check PrioSTRIP SR, Prionics
brings to the market the first test to achieve high diagnostic sensitivity on
preclinical TSE cases. The test was approved today by the European Commission
for use in TSE testing in small ruminants*. The Prionics®-Check PrioSTRIP SR can
detect scrapie earlier than conventional tests and will therefore significantly
contribute to TSE control programs.
The Prionics®-Check PrioSTRIP SR was extensively tested in a laboratory
evaluation directed by the European Commission. The product fulfilled all the
requirements of the EU evaluation and has now been approved as a rapid test for
detection of TSE in the central nervous system of small ruminants (i.e. sheep
and goats).
Superior detection of preclinical scrapie
The Prionics®-CHECK PrioSTRIP SR detected EU reference samples of classical
and atypical scrapie in sheep and goats as well as BSE in sheep with a
sensitivity and specificity of 100%. The Prionics®- CHECK PrioSTRIP SR also
proved to be the first test kit to achieve a high diagnostic sensitivity on
preclinical TSE cases. Most importantly, the test can detect infection as early
as 7 months post exposure, which is earlier - during the incubation period -
than the reference tests. “Early detection of scrapie is a critical factor in
disease control programs” says Ernst Zollinger, Head of Marketing and Sales at
Prionics. “In contrast to BSE, scrapie is an outbreak disease which could not be
eliminated for centuries. The earlier the infection is detected means that the
costs associated with managing scrapie can be minimized.”
PrioSTRIP®SR: Fast and simple
The Prionics®-Check PrioSTRIP SR is not only the most sensitive test, but
is also the fastest and simplest sheep TSE test on the market, making it an
excellent tool to monitor the incidence of TSE in small ruminants. This fast
high throughput laboratory assay delivers results in just over one hour and is
based on immunochromatography, using antibody-mediated detection of scrapie and
BSE prions. The Prionics®-Check PrioSTRIP SR is an economical test as it
requires only minimal laboratory equipment and produces little waste. This fast
and convenient test uses the same technology as the established and successful
PrioSTRIP® test for BSE in cattle, meaning that the same test principle can be
used for the detection of BSE in cattle and TSE in small ruminants.
About TSE in small ruminants
Small ruminants (sheep and goats) can be infected with scrapie or BSE under
natural circumstances. While scrapie is thought to be non-infectious to humans,
it is unclear whether BSE in sheep and goats could cause Creutzfeldt-Jakob
disease in humans, similar to that of BSE in cattle. Small ruminant testing
programs, initiated by the European Community to identify the incidence of TSE
in sheep and goats, are ongoing.
About Prionics
Prionics AG, based in Zurich, Switzerland, is a leading provider of farm
animal diagnostics and is a recognized center of expertise in BSE and prion
diseases. Prionics produces and markets innovative diagnostic solutions for
major farm animal diseases, aiding in the protection of consumer health.
Prionics is the main sponsor of the 16th International Symposium of the
World Association of Veterinary Laboratory Diagnosticians in Berlin June 5-8,
2013.
For more information please visit www.prionics.com or contact:
Marjan van der Haar, PhD
Marketing Communications
Tel: +41 44 200 20 57 / +41 79 352 53 16
Email: media@prionics.com
New test to combat scrapie and mad cow disease in sheep and goats
Zurich, November 14, 2012 - An innovative new test is now available to
detect TSE (scrapie and mad cow disease) in sheep and goats. With the
Prionics®-Check PrioSTRIP SR, Prionics brings to the market the first test to
achieve high diagnostic sensitivity on preclinical TSE cases. The test was
approved today by the European Commission for use in TSE testing in small
ruminants*. The Prionics®-Check PrioSTRIP SR can detect scrapie earlier than
conventional tests and will therefore significantly contribute to TSE control
programs.
The Prionics®-Check PrioSTRIP SR was extensively tested in a laboratory
evaluation directed by the European Commission. The product fulfilled all the
requirements of the EU evaluation and has now been approved as a rapid test for
detection of TSE in the central nervous system of small ruminants (i.e. sheep
and goats).
Superior detection of preclinical scrapie
The Prionics®-CHECK PrioSTRIP SR detected EU reference samples of classical
and atypical scrapie in sheep and goats as well as BSE in sheep with a
sensitivity and specificity of 100%. The Prionics®-CHECK PrioSTRIP SR also
proved to be the first test kit to achieve a high diagnostic sensitivity on
preclinical TSE cases. Most importantly, the test can detect infection as early
as 7 months post exposure, which is earlier - during the incubation period -
than the reference tests. “Early detection of scrapie is a critical factor in
disease control programs” says Ernst Zollinger, Head of Marketing and Sales at
Prionics. “In contrast to BSE, scrapie is an outbreak disease which could not be
eliminated for centuries. The earlier the infection is detected means that the
costs associated with managing scrapie can be minimized.”
PrioSTRIP® SR: Fast and simple
The Prionics®-Check PrioSTRIP SR is not only the most sensitive test, but
is also the fastest and simplest sheep TSE test on the market, making it an
excellent tool to monitor the incidence of TSE in small ruminants. This fast
high throughput laboratory assay delivers results in just over one hour and is
based on immunochromatography, using antibody-mediated detection of scrapie and
BSE prions. The Prionics®-Check PrioSTRIP SR is an economical test as it
requires only minimal laboratory equipment and produces little waste. This fast
and convenient test uses the same technology as the established and successful
PrioSTRIP® test for BSE in cattle, meaning that the same test principle can be
used for the detection of BSE in cattle and TSE in small ruminants.
About TSE in small ruminants
Small ruminants (sheep and goats) can be infected with scrapie or BSE under
natural circumstances. While scrapie is thought to be non-infectious to humans,
it is unclear whether BSE in sheep and goats could cause Creutzfeldt-Jakob
disease in humans, similar to that of BSE in cattle. Small ruminant testing
programs, initiated by the European Community to identify the incidence of TSE
in sheep and goats, are ongoing.
>>> Superior detection of preclinical scrapie The Prionics®-CHECK
PrioSTRIP SR detected EU reference samples of classical and atypical scrapie in
sheep and goats as well as BSE in sheep with a sensitivity and specificity of
100%.
a test is only as good as the ones giving that test. your country can be
full of TSEs, and you can have a TSE prion test with a specificity of 100%, and
still not find much of anything, only by chance, when part of your 2004 enhanced
BSE surveillance program consisted of only testing healthy cattle brains. case
in point ;
Owner and Corporation Plead Guilty to Defrauding Bovine Spongiform
Encephalopathy (BSE) Surveillance Program
An Arizona meat processing company and its owner pled guilty in February
2007 to charges of theft of Government funds, mail fraud, and wire fraud. The
owner and his company defrauded the BSE Surveillance Program when they falsified
BSE Surveillance Data Collection Forms and then submitted payment requests to
USDA for the services. In addition to the targeted sample population (those
cattle that were more than 30 months old or had other risk factors for BSE), the
owner submitted to USDA, or caused to be submitted, BSE obex (brain stem)
samples from healthy USDA-inspected cattle. As a result, the owner fraudulently
received approximately $390,000. Sentencing is scheduled for May 2007.
snip...
Topics that will be covered in ongoing or planned reviews under Goal 1
include:
soundness of BSE maintenance sampling (APHIS),
implementation of Performance-Based Inspection System enhancements for
specified risk material (SRM) violations and improved inspection controls over
SRMs (FSIS and APHIS),
snip...
The findings and recommendations from these efforts will be covered in
future semiannual reports as the relevant audits and investigations are
completed.
4 USDA OIG SEMIANNUAL REPORT TO CONGRESS FY 2007 1st Half
-MORE Office of the United States Attorney District of Arizona FOR
IMMEDIATE RELEASE For Information Contact Public Affairs February 16, 2007 WYN
HORNBUCKLE Telephone: (602) 514-7625 Cell: (602) 525-2681
CORPORATION AND ITS PRESIDENT PLEAD GUILTY TO DEFRAUDING GOVERNMENTS MAD
COW DISEASE SURVEILLANCE PROGRAM
PHOENIX -- Farm Fresh Meats, Inc. and Roland Emerson Farabee, 55, of
Maricopa, Arizona, pleaded guilty to stealing $390,000 in government funds, mail
fraud and wire fraud, in federal district court in Phoenix. U.S. Attorney Daniel
Knauss stated, The integrity of the system that tests for mad cow disease relies
upon the honest cooperation of enterprises like Farm Fresh Meats. Without that
honest cooperation, consumers both in the U.S. and internationally are at risk.
We want to thank the USDAs Office of Inspector General for their continuing
efforts to safeguard the public health and enforce the law. Farm Fresh Meats
and Farabee were charged by Information with theft of government funds, mail
fraud and wire fraud. According to the Information, on June 7, 2004, Farabee, on
behalf of Farm Fresh Meats, signed a contract with the U.S. Department of
Agriculture (the USDA Agreement) to collect obex samples from cattle at high
risk of mad cow disease (the Targeted Cattle Population). The Targeted Cattle
Population consisted of the following cattle: cattle over thirty months of age;
nonambulatory cattle; cattle exhibiting signs of central nervous system
disorders; cattle exhibiting signs of mad cow disease; and dead cattle. Pursuant
to the USDA Agreement, the USDA agreed to pay Farm Fresh Meats $150 per obex
sample for collecting obex samples from cattle within the Targeted Cattle
Population, and submitting the obex samples to a USDA laboratory for mad cow
disease testing. Farm Fresh Meats further agreed to maintain in cold storage the
sampled cattle carcasses and heads until the test results were received by Farm
Fresh Meats.
Evidence uncovered during the governments investigation established that
Farm Fresh Meats and Farabee submitted samples from cattle outside the Targeted
Cattle Population. Specifically, Farm Fresh Meats and Farabee submitted, or
caused to be submitted, obex samples from healthy, USDA inspected cattle, in
order to steal government moneys.
Evidence collected also demonstrated that Farm Fresh Meats and Farabee
failed to maintain cattle carcasses and heads pending test results and falsified
corporate books and records to conceal their malfeasance. Such actions, to the
extent an obex sample tested positive (fortunately, none did), could have
jeopardized the USDAs ability to identify the diseased animal and pinpoint its
place of origin. On Wednesday, February 14, 2007, Farm Fresh Meats and Farabee
pleaded guilty to stealing government funds and using the mails and wires to
effect the scheme. According to their guilty pleas:
(a) Farm Fresh Meats collected, and Farabee directed others to collect,
obex samples from cattle outside the Targeted Cattle Population, which were not
subject to payment by the USDA;
(b) Farm Fresh Meats 2 and Farabee caused to be submitted payment requests
to the USDA knowing that the requests were based on obex samples that were not
subject to payment under the USDA Agreement;
(c) Farm Fresh Meats completed and submitted, and Farabee directed others
to complete and submit, BSE Surveillance Data Collection Forms to the USDAs
testing laboratory that were false and misleading;
(d) Farm Fresh Meats completed and submitted, and Farabee directed others
to complete and submit, BSE Surveillance Submission Forms filed with the USDA
that were false and misleading;
(e) Farm Fresh Meats falsified, and Farabee directed others to falsify,
internal Farm Fresh Meats documents to conceal the fact that Farm Fresh Meats
was seeking and obtaining payment from the USDA for obex samples obtained from
cattle outside the Targeted Cattle Population; and
(f) Farm Fresh Meats failed to comply with, and Farabee directed others to
fail to comply with, the USDA Agreement by discarding cattle carcasses and heads
prior to receiving BSE test results. A conviction for theft of government funds
carries a maximum penalty of 10 years imprisonment. Mail fraud and wire fraud
convictions carry a maximum penalty of 20 years imprisonment. Convictions for
the above referenced violations also carry a maximum fine of $250,000 for
individuals and $500,000 for organizations. In determining an actual sentence,
Judge Earl H. Carroll will consult the U.S. Sentencing Guidelines, which provide
appropriate sentencing ranges. The judge, however, is not bound by those
guidelines in determining a sentence.
Sentencing is set before Judge Earl H. Carroll on May 14, 2007. The
investigation in this case was conducted by Assistant Special Agent in Charge
Alejandro Quintero, United States Department of Agriculture, Office of Inspector
General. The prosecution is being handled by Robert Long, Assistant U.S.
Attorney, District of Arizona, Phoenix. CASE NUMBER: CR-07-00160-PHX-EHC RELEASE
NUMBER: 2007-051(Farabee) # # #
Friday, May 4, 2012
May 2, 2012: Update from APHIS Regarding a Detection of Bovine Spongiform
Encephalopathy (BSE) in the United States
PAUL BROWN COMMENT TO ME ON THIS ISSUE
Tuesday, September 12, 2006 11:10 AM
"Actually, Terry, I have been critical of the USDA handling of the mad cow
issue for some years, and with Linda Detwiler and others sent lengthy detailed
critiques and recommendations to both the USDA and the Canadian Food Agency."
........TSS
OR, what the Honorable Phyllis Fong of the OIG found ;
Audit Report Animal and Plant Health Inspection Service Bovine Spongiform
Encephalopathy (BSE) Surveillance Program  Phase II and Food Safety and
Inspection Service
Controls Over BSE Sampling, Specified Risk Materials, and Advanced Meat
Recovery Products - Phase III
Report No. 50601-10-KC January 2006
Finding 2 Inherent Challenges in Identifying and Testing High-Risk Cattle
Still Remain
Tuesday, January 1, 2008
BSE OIE USDA
Subject: OIE BSE RECOMMENDATION FOR USA, bought and paid for by your local
cattle dealers i.e. USDA
Date: May 14, 2007 at 9:00 am PST
OIE BSE RECOMMENDATION FOR USA, bought and paid for by your local cattle
dealers i.e. USDA
STATEMENT BY DR. RON DEHAVEN REGARDING OIE RISK RECOMMENDATION
March 9, 2007
Tuesday, November 02, 2010
IN CONFIDENCE
The information contained herein should not be disseminated further except
on the basis of "NEED TO KNOW".
BSE - ATYPICAL LESION DISTRIBUTION (RBSE 92-21367) statutory (obex only)
diagnostic criteria CVL 1992
2009 UPDATE ON ALABAMA AND TEXAS MAD COWS 2005 and 2006
Comments on technical aspects of the risk assessment were then submitted to
FSIS.
Comments were received from Food and Water Watch, Food Animal Concerns
Trust (FACT), Farm Sanctuary, R-CALF USA, Linda A Detwiler, and Terry S.
Singeltary.
This document provides itemized replies to the public comments received on
the 2005 updated Harvard BSE risk assessment. Please bear the following points
in mind:
Owens, Julie
From: Terry S. Singeltary Sr. [flounder9@verizon.net]
Sent: Monday, July 24, 2006 1:09 PM
To: FSIS RegulationsComments
Subject: [Docket No. FSIS-2006-0011] FSIS Harvard Risk Assessment of Bovine
Spongiform Encephalopathy (BSE)
Page 1 of 98
FSIS, USDA, REPLY TO SINGELTARY
U.S.A. 50 STATE BSE MAD COW CONFERENCE CALL Jan. 9, 2001
2012 atypical L-type BSE BASE California reports
Saturday, August 4, 2012
Final Feed Investigation Summary - California BSE Case - July 2012
SUMMARY REPORT CALIFORNIA BOVINE SPONGIFORM ENCEPHALOPATHY CASE
INVESTIGATION JULY 2012
Summary Report BSE 2012
Executive Summary
Saturday, August 4, 2012
Update from APHIS Regarding Release of the Final Report on the BSE
Epidemiological Investigation
CENSORSHIP IS A TERRIBLE THING $$$
Canada has had a COVER-UP policy of mad cow disease since about the 17th
case OR 18th case of mad cow disease. AFTER THAT, all FOIA request were ignored
$$$
THIS proves there is indeed an epidemic of mad cow disease in North
America, and it has been covered up for years and years, if not for decades, and
it’s getting worse $$$
Thursday, February 10, 2011
TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHY REPORT UPDATE CANADA FEBRUARY 2011
and how to hide mad cow disease in Canada Current as of: 2011-01-31
Wednesday, August 11, 2010
REPORT ON THE INVESTIGATION OF THE SIXTEENTH CASE OF BOVINE SPONGIFORM
ENCEPHALOPATHY (BSE) IN CANADA
Thursday, August 19, 2010
REPORT ON THE INVESTIGATION OF THE SEVENTEENTH CASE OF BOVINE SPONGIFORM
ENCEPHALOPATHY (BSE) IN CANADA
Friday, March 4, 2011
Alberta dairy cow found with mad cow disease
Reasons for the New Regulation Order No. 23 (as well as amending Order No.
149) of the State Committee for Veterinary Medicine name BSE as the reason for
new import requirement. The legal title for Order No. 23 is "On Urgent Measures
Aimed at Prevention and Elimination of BSE and Other Prion Infections in
Cattle”. Neither Order explains how the threat of introduction of BSE can be
addressed through the inspection of producers of all products of animal origin
including fish, dairy products, poultry and pork. It is not clear what other
concerns are addressed through the proposed inspections. Formal Notification of
Trading Partners On August 3rd, Ukraine's Notification and Enquiry Point issued
a legal Notification G/SPS/N/UKR/3/Rev.1 found on the Official WTO Website
(Committee on Sanitary and Phytosanitary Measures)
Thursday, March 29, 2012
atypical Nor-98 Scrapie has spread from coast to coast in the USA 2012
NIAA Annual Conference April 11-14, 2011San Antonio, Texas
Monday, November 30, 2009
USDA AND OIE COLLABORATE TO EXCLUDE ATYPICAL SCRAPIE NOR-98 ANIMAL HEALTH
CODE
Thursday, August 12, 2010
Seven main threats for the future linked to prions
First threat
The TSE road map defining the evolution of European policy for protection
against prion diseases is based on a certain numbers of hypotheses some of which
may turn out to be erroneous. In particular, a form of BSE (called atypical
Bovine Spongiform Encephalopathy), recently identified by systematic testing in
aged cattle without clinical signs, may be the origin of classical BSE and thus
potentially constitute a reservoir, which may be impossible to eradicate if a
sporadic origin is confirmed. ***Also, a link is suspected between atypical BSE
and some apparently sporadic cases of Creutzfeldt-Jakob disease in humans. These
atypical BSE cases constitute an unforeseen first threat that could sharply
modify the European approach to prion diseases.
Second threat
snip...
EFSA Journal 2011 The European Response to BSE: A Success Story
This is an interesting editorial about the Mad Cow Disease debacle, and
it's ramifications that will continue to play out for decades to come ;
Monday, October 10, 2011
EFSA Journal 2011 The European Response to BSE: A Success Story
snip...
EFSA and the European Centre for Disease Prevention and Control (ECDC)
recently delivered a scientific opinion on any possible epidemiological or
molecular association between TSEs in animals and humans (EFSA Panel on
Biological Hazards (BIOHAZ) and ECDC, 2011). This opinion confirmed Classical
BSE prions as the only TSE agents demonstrated to be zoonotic so far but the
possibility that a small proportion of human cases so far classified as
"sporadic" CJD are of zoonotic origin could not be excluded. Moreover,
transmission experiments to non-human primates suggest that some TSE agents in
addition to Classical BSE prions in cattle (namely L-type Atypical BSE,
Classical BSE in sheep, transmissible mink encephalopathy (TME) and chronic
wasting disease (CWD) agents) might have zoonotic potential.
snip...
see follow-up here about North America BSE Mad Cow TSE prion risk factors,
and the ever emerging strains of Transmissible Spongiform Encephalopathy in many
species here in the USA, including humans ;
2011 Monday, September 26, 2011
L-BSE BASE prion and atypical sporadic CJD
Saturday, March 5, 2011
MAD COW ATYPICAL CJD PRION TSE CASES WITH CLASSIFICATIONS PENDING ON THE
RISE IN NORTH AMERICA
Wednesday, August 01, 2012
Behavioural and Psychiatric Features of the Human Prion Diseases:
Experience in 368 Prospectively Studied Patients
Monday, August 06, 2012
Atypical neuropathological sCJD-MM phenotype with abundant white matter
Kuru-type plaques sparing the cerebellar cortex
Tuesday, June 26, 2012
Creutzfeldt Jakob Disease Human TSE report update North America, Canada,
Mexico, and USDA PRION UNIT as of May 18, 2012
type determination pending Creutzfeldt Jakob Disease (tdpCJD), is on the
rise in Canada and the USA
Friday, August 24, 2012
Iatrogenic prion diseases in humans: an update
Monday, July 23, 2012
The National Prion Disease Pathology Surveillance Center July 2012
OR-10: Variably protease-sensitive prionopathy is transmissible in bank
voles
Romolo Nonno,1 Michele Di Bari,1 Laura Pirisinu,1 Claudia D’Agostino,1
Stefano Marcon,1 Geraldina Riccardi,1 Gabriele Vaccari,1 Piero Parchi,2 Wenquan
Zou,3 Pierluigi Gambetti,3 Umberto Agrimi1 1Istituto Superiore di Sanità; Rome,
Italy; 2Dipartimento di Scienze Neurologiche, Università di Bologna; Bologna,
Italy; 3Case Western Reserve University; Cleveland, OH USA
Background. Variably protease-sensitive prionopathy (VPSPr) is a recently
described “sporadic”neurodegenerative disease involving prion protein
aggregation, which has clinical similarities with non-Alzheimer dementias, such
as fronto-temporal dementia. Currently, 30 cases of VPSPr have been reported in
Europe and USA, of which 19 cases were homozygous for valine at codon 129 of the
prion protein (VV), 8 were MV and 3 were MM. A distinctive feature of VPSPr is
the electrophoretic pattern of PrPSc after digestion with proteinase K (PK).
After PK-treatment, PrP from VPSPr forms a ladder-like electrophoretic pattern
similar to that described in GSS cases. The clinical and pathological features
of VPSPr raised the question of the correct classification of VPSPr among prion
diseases or other forms of neurodegenerative disorders. Here we report
preliminary data on the transmissibility and pathological features of VPSPr
cases in bank voles.
Materials and Methods. Seven VPSPr cases were inoculated in two genetic
lines of bank voles, carrying either methionine or isoleucine at codon 109 of
the prion protein (named BvM109 and BvI109, respectively). Among the VPSPr cases
selected, 2 were VV at PrP codon 129, 3 were MV and 2 were MM. Clinical
diagnosis in voles was confirmed by brain pathological assessment and western
blot for PK-resistant PrPSc (PrPres) with mAbs SAF32, SAF84, 12B2 and 9A2.
Results. To date, 2 VPSPr cases (1 MV and 1 MM) gave positive transmission
in BvM109. Overall, 3 voles were positive with survival time between 290 and 588
d post inoculation (d.p.i.). All positive voles accumulated PrPres in the form
of the typical PrP27–30, which was indistinguishable to that previously observed
in BvM109 inoculated with sCJDMM1 cases.
In BvI109, 3 VPSPr cases (2 VV and 1 MM) showed positive transmission until
now. Overall, 5 voles were positive with survival time between 281 and 596
d.p.i.. In contrast to what observed in BvM109, all BvI109 showed a GSS-like
PrPSc electrophoretic pattern, characterized by low molecular weight PrPres.
These PrPres fragments were positive with mAb 9A2 and 12B2, while being negative
with SAF32 and SAF84, suggesting that they are cleaved at both the C-terminus
and the N-terminus. Second passages are in progress from these first successful
transmissions.
Conclusions. Preliminary results from transmission studies in bank voles
strongly support the notion that VPSPr is a transmissible prion disease.
Interestingly, VPSPr undergoes divergent evolution in the two genetic lines of
voles, with sCJD-like features in BvM109 and GSS-like properties in
BvI109.
The discovery of previously unrecognized prion diseases in both humans and
animals (i.e., Nor98 in small ruminants) demonstrates that the range of prion
diseases might be wider than expected and raises crucial questions about the
epidemiology and strain properties of these new forms. We are investigating this
latter issue by molecular and biological comparison of VPSPr, GSS and Nor98.
Wednesday, March 28, 2012
VARIABLY PROTEASE-SENSITVE PRIONOPATHY IS TRANSMISSIBLE, price of prion
poker goes up again $
*** The discovery of previously unrecognized prion diseases in both humans
and animals (i.e., Nor98 in small ruminants) demonstrates that the range of
prion diseases might be wider than expected and raises crucial questions about
the epidemiology and strain properties of these new forms. We are investigating
this latter issue by molecular and biological comparison of VPSPr, GSS and
Nor98.
AS OF AUGUST 2012 ;
CJD UPDATE USA
1 Listed based on the year of death or, if not available, on year of
referral; 2 Cases with suspected prion disease for which brain tissue and/or
blood (in familial cases) were submitted; 3 Disease acquired in the United
Kingdom; 4 Disease was acquired in the United Kingdom in one case and in Saudi
Arabia in the other case; *** 5 Includes 8 cases in which the diagnosis is
pending, and 18 inconclusive cases; *** 6 Includes 10 (9 from 2012) cases with
type determination pending in which the diagnosis of vCJD has been excluded. ***
The Sporadic cases include 16 cases of sporadic Fatal Insomnia (sFI) and 42
cases of Variably Protease-Sensitive Prionopathy (VPSPr) and 2224 cases of
sporadic Creutzfeldt-Jakob disease (sCJD).
Sunday, September 23, 2012
EU-Approved Rapid Tests for Bovine Spongiform Encephalopathy Detect
Atypical Forms: A Study for Their Sensitivities
**** Tuesday, November 6, 2012
Transmission of New Bovine Prion to Mice, Atypical Scrapie, BSE, and
Sporadic CJD, November-December 2012 update
TSS
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